The Department of Health’s National Institute for Health Research invites applications for its commissioned call for proposals under its efficacy and mechanism evaluation programme. Proposals may address the following topics:

•14/200 bone metabolism including parathyroid disorders;

•14/201 inflammatory bowel disease;

•14/202 mechanisms of action of health intervention;

•14/203 mesothelioma;

•14/204 novel endoscopic optical imaging interventions and technologies;

•14/205 mechanisms of isolated traumatic brain injury.

Researchers in England, Northern Ireland, Scotland and Wales are eligible to apply for funding.